What are some other side effects of Meropenem? Used in the systemic treatment of infections. doi: 10.1093/clinids/24.supplement_2.s266. Meropenem. Meropenem may also interact with some other medications. Pharmacokinetics of meropenem compared to imipenem-cilastatin in young, healthy males. Meropenem has been reported to be excreted in human milk. Vomiting Bluish lips or skin 2. chills 3. cold, clammy skin 4. confusion 5. dizziness 6. fainting 7. fast heartbeat 8. fast, weak pulse 9. fever 10. itching, skin rash 11. lightheadedness 12. rapid, shallow breathing 13. sweating The pharmacokinetic parameter … 5 mg/kg PO q24h (cats)10–20 mg/kg q24h (dogs) ... Meropenem: 8.5 mg/kg SC/IV q 12 (SC) or 8 (IV)h: Reserve for treatment of multidrug-resistant infections, particularly those caused by Enterobacteriaceae or Pseudomonas aeruginosa. has been prescribed for your pet for the treatment of an infection caused by susceptible bacteria because other less expensive antibiotics were not effective or unacceptable because of their adverse effects. Find patient medical information for Meropenem Intravenous on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. If experienced, these tend to have a Severe expression 1. Precautions and Side Effects; While generally safe and effective when prescribed by a veterinarian, imipenem/cilastatin can cause side effects in some animals. Cats Label dose: 10-15mg/kg PO or IV q12h: For serious anaerobic infections: 25 – 50 mg/kg PO or IV q12h: For enteritis caused by Clostridium difficile: 62.5mg/cat PO q12h for 5d: For metronidazole benzoate: 25 mg/kg PO q12h : Dogs Label dose: 10-15mg/kg PO q12h: Brand Name(s) Flagyl® Background. A review of its antibacterial activity, pharmacokinetic properties and clinical efficacy. Medically reviewed by Drugs.com. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Animal ages ranged from 0 to 19 years of age, with a median of 11 years. "Comparative Review of the Carbapenems." Headache 5. J Antimicrob Chemother 36(suppl a (1995): 145-56, 15. Therapeutic uses, prescribing information and product availability may vary between countries. Meropenem. [Ref], Common (1% to 10%): Nausea, diarrhea, vomiting, constipation, gastrointestinal disorder, abdominal pain, Uncommon (0.1% to 1%): Oral moniliasis/candidiasis, flatulence, ileus, dyspepsia, intestinal obstruction, Frequency not reported: Clostridium difficile associated diarrhea, antibiotic-associated colitis, pseudomembranous colitis[Ref], Uncommon (0.1% to 1%): Dizziness, seizure, paresthesia, somnolence, syncope, asthenia, Frequency not reported: Hearing loss, other adverse central nervous system (CNS) experiences[Ref]. Learn about the prescription drug meropenem (Merrem) used to treat a variety of bacterial infections. From: Side Effects of Drugs Annual, 2011. eCollection 2019. Huizinga WK, Warren BL, Baker LW, Valleur P, Pezet DM, Hoogkamp-Korstanjep JA, Karran SJ "Antibiotic monotherapy with meropenem in the surgical management of intra-abdominal infections." Seizures and other adverse CNS experiences have been reported. All medicines can have side effects. Approximately 70% of meropenem is excreted via the kidneys, thus dosage adjustments are required for patients with renal impairment. Meropenem (Merrem) use in cats, is it safe? The pharmacology of meropenem, a new carbapenem antibiotic. Clin Infect Dis 36 (2003): E149-E151. [Ref], Common (1% to 10%): Peripheral vascular disorder, Uncommon (0.1% to 1%): Heart failure, heart arrest, tachycardia, hypertension, myocardial infarction, pulmonary embolus, bradycardia, hypotension[Ref], Common (1% to 10%): Increased transaminases, Uncommon (0.1% to 1%): Increased AST, increased ALT, increased bilirubin, hepatic failure, cholestatic jaundice/jaundice[Ref], Common (1% to 10%): Hypoglycemia, increased alkaline phosphatase, increased lactate dehydrogenase, Uncommon (0.1% to 1%): Anorexia, hypervolemia, hypokalemia[Ref], Uncommon (0.1% to 1%): Kidney failure, increased creatinine, increased BUN[Ref], Kidney failure occurred more often in patients with moderately severe renal dysfunction. Clin Pharmacokinet. Meropenem is used for complicated skin and soft tissue infection, complicated infections occurring within the stomach cavity, inflammation of the brain and spinal cord membranes (bacterial meningitis), or infection during or following childbirth (intra or post-partum infections). Predictive Performance of Physiologically Based Pharmacokinetic and Population Pharmacokinetic Modeling of Renally Cleared Drugs in Children. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Applies to meropenem: intravenous powder for injection, intravenous solution, In clinical trials (n=2904), this drug was discontinued in 1.2% of patients due to side effects; 5 deaths were possibly drug-related. Side effects not requiring immediate medical attention. In case of any doubt consult your doctor or pharmacist. Drugs 67 (2007): 1027-1052, 4. Normalement, c'est un médecin ou une infirmière qui vous administrera MEROPENEM MYLAN 1 g, poudre pour solution injectable/pour perfusion. Common side effects include nausea, diarrhea, constipation, headache, rash, and pain at the site of injection. Cats are very susceptible to the vestibular effects of amikacin. Many Enterobacteriaceaethat are resistant to other antimicrobials will be susceptible to meropenem; therefore, use should be strictly reserved for infections caused by organisms that are resistant to other antimicrobial choices. Imipenem/cilastatin: rationale for a fixed combination. Antimicrob Agents Chemother 42 (1998): 1233-8, 8. O 0, 3. Germovsek E, Lutsar I, Kipper K, Karlsson MO, Planche T, Chazallon C, Meyer L, Trafojer UMT, Metsvaht T, Fournier I, Sharland M, Heath P, Standing JF; NeoMero Consortium. Anemia If experienced, these tend to have a Less Severe expression 1. Adequate and well-controlled studies of this drug in pregnant women are lacking, and this drug should be used during pregnancy only if clearly needed. Please enable it to take advantage of the complete set of features! This site needs JavaScript to work properly. Clin Infect Dis 24 ( Suppl (1997): s222-30, 9. Eur J Drug Metab Pharmacokinet. 1991 Feb;10(2):85-8. doi: 10.1007/BF01964413. Drug information provided by: IBM Micromedex. Epub 2016 Aug 27. USA.gov. [Ref], Common (1% to 10%): Pain, inflammation, sepsis/septicemia, shock, accidental injury, Uncommon (0.1% to 1%): Chest pain, fever, back pain, chills, pelvic pain, peripheral edema, abdominal enlargement[Ref], Common (1% to 10%): Inflammation at the injection site, phlebitis/thrombophlebitis, pain at the injection site, Uncommon (0.1% to 1%): Injection site reactions, edema at the injection site[Ref], Common (1% to 10%): Rash (including diaper/nappy area moniliasis), pruritus, Uncommon (0.1% to 1%): Urticaria, sweating, skin ulcer, Postmarketing reports: Toxic epidermal necrolysis, Stevens-Johnson syndrome, angioedema, erythema multiforme, severe skin reactions[Ref], Common (1% to 10%): Apnea, pharyngitis, pneumonia, Uncommon (0.1% to 1%): Respiratory disorder, dyspnea, pleural effusion, asthma, increased cough, hypoxia, lung edema, Frequency not reported: Respiratory failure[Ref], Heart failure occurred more often in patients with moderately severe renal dysfunction.  |  Cependant, certains patients, parents et soignants sont formés pour administrer MEROPENEM MYLAN 1 g, poudre … COPD Study Group." Those who are allergic to other β-lactam antibiotics are more likely to be allergic to meropenem as well. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: Headache. Infection 24 (1996): 473-9, 11. General Description: Meropenem. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. 1985 Jul-Aug;7 Suppl 3:S447-51. Infection 24 (1996): 480-4, 10. Paquet P, Jacob E, Damas P, Pierard GE "Recurrent fatal drug-induced toxic epidermal necrolysis (Lyell's syndrome) after putative beta-lactam cross-reactivity: Case report and scrutiny of antibiotic imputability." 2019 Jun 13;15(6):e1007117. One of the adverse effects caused from imipenem therapy is seizures. The IV LD50 of meropenem in rodents is greater than 2000 mg/kg. They have occurred most commonly in patients with CNS disorders (e.g., history of seizures, brain lesions) or with bacterial meningitis and/or renal dysfunction.  |  Meropenem, one of the newest of the carbapenem class of drugs has antibacterial activity approximately equal to, or greater than imipenem. Hemsell DL, Martens MG, Faro S, Gall S, Mcgregor JA "A multicenter study comparing intravenous meropenem with clindamycin plus gentamicin for the treatment of acute gynecologic and obstetric pelvic infections in hospitalized women." J Antimicrob Chemother 36(suppl a (1995): 121-33, 18. Meropenem (Meropenem Hikma®; Hikma Pharma, Gräfelfing, Germany) was administered as a prolonged infusion over 4 h using a syringe pump. PLoS Comput Biol. Along with its needed effects, meropenem may cause some unwanted effects. CPT Pharmacometrics Syst Pharmacol. The urinary recovery of meropenem is as high as that of imipenem in combination with cilastatin, an inhibitor of renal dehydropeptidase. It is the same drug class as Imipenem. is supplied in 20 mL and 30 mL injection vials containing sufficient meropenem to deliver 500 mg or 1 g, respectively. Veterinarian: Dr. Susan, Veterinarian replied 9 years ago. Meropenem. Meropenem is a carbapenem antibiotic that appears to be widely distributed in tissues and is eliminated by both excretion and metabolism. O 0, 14. It inhibits bacterial cell wall synthesis by binding to several penicillin-binding proteins (PBPs) in gram-negative and gram-positive bacteria resulting in cell wall assembly arrest and eventually bacterial cell lysis. Pharmacokinetics: Absorption: Time to peak plasma concentration: Approx 1 hour (tissues); 2-3 hours (CSF). Adverse Side Effects. Plasma and Renal Cortex Meropenem Concentrations in Patients Undergoing Percutaneous Renal Biopsy. Am J Health Syst Pharm 69 (2012): 1109, 19. Get the latest research from NIH: https://www.nih.gov/coronavirus. Available for Android and iOS devices. Side Effects; Products and services. Development of a physiologically-based pharmacokinetic pediatric brain model for prediction of cerebrospinal fluid drug concentrations and the influence of meningitis. J Antimicrob Chemother. 1. All drugs may cause side effects. Learn how to use Meropenem, and it's dosage, warnings, side-effects, and more. Sepúlveda RA, Downey P, Soto D, Wong KY, Leung YC, So LY, Andresen M. Biomed Res Int. Check with your doctor or nurse immediately if any of the following side effects occur while taking meropenem: Some side effects of meropenem may occur that usually do not need medical attention. Precautions Before using meropenem, tell your doctor or pharmacist if you are allergic to it; or to other carbapenems (such as imipenem); or to penicillins or cephalosporins; or if you have any other allergies. Meropenem injection is used to treat infections caused by bacteria. We comply with the HONcode standard for trustworthy health information -, unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness, vomiting of blood or material that looks like coffee grounds, white patches in the mouth, tongue, or throat, blistering, peeling, or loosening of the skin, holding false beliefs that cannot be changed by fact, large, hive-like swelling on the face, eyelids, tongue, throat, hands, legs, feet, or genitals, red skin lesions, often with a purple center, seeing, hearing, or feeling things that are not there, sores, ulcers, or white spots in the mouth or on the lips, unusual excitement, nervousness, or restlessness, redness and swelling at the injection site, redness, swelling, or soreness of the tongue, excess air or gas in the stomach or bowels. Description: Meropenem is a β-lactam antibiotic. Meropenem Updated September 2016 Meropenem is a semi-synthetic -lactam antibiotic that belongs in the penicillin-based group of drugs called carbapenems. Ralph ED, John M, Rieder MJ, Bombassaro AM "Serum Sickness-like Reaction Possibly Associated with Meropenem Use." Carbapenem resistance is a growing problem in human medicine and is expecte… Clin Ther 28 (2006): 1164-74, 6. Sometimes they are serious, most of the time they are not. 2019 Nov 19;2019:1368397. doi: 10.1155/2019/1368397. Merrem IV; Descriptions. The median age of dogs was 10 years (range, 1‐14), and the median age of cats was 13 years (range, 0‐19). Cerner Multum, Inc. "UK Summary of Product Characteristics." Kimberly A. Toussaint, Jason C. Gallagher, in Side Effects of Drugs Annual, 2014. However, clinical trials are necessary to confirm clinical efficacy of the proposed dosage regimen. Crit Care Med 30 (2002): 2580-3, 20. J Antimicrob Chemother 36(suppl a (1995): 179-89, 16. doi: 10.1093/clinids/7.supplement_3.s447. Verscheijden LFM, Koenderink JB, de Wildt SN, Russel FGM. Storage of the Drug. This is especially important if your pet is currently taking probenecid. The pharmacokinetic parameters for meropenem are similar to those for imipenem/cilastatin, with the exception of meropenem's smaller volume of distribution. Merrem (meropenem)." Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. infections in cystic fibrosis patients." Kempf P, Bauernfeind A, Muller A, Blum J "Meropenem monotherapy versus cefotaxime plus metronidazole combination treatment for serious intra-abdominal infections." J Antimicrob Chemother 24(suppl a (1989): 311-20, 12. Effects were seen in acute toxicity studies in rodent at doses exceeding 1000 mg/kg. Bax RP, Bastain W, Featherstone A, Wilkinson DM, Hutchison M, Haworth SJ "The pharmacokinetics of meropenem in volunteers." Clipboard, Search History, and several other advanced features are temporarily unavailable. Meropenem injection may cause side effects. Meropenem. 2019 Jun;44(3):433-436. doi: 10.1007/s13318-018-0524-4. Drugs 68 (2008): 803-38, 5. Amikacin can be stored at room temperature and is stable for up to 2 years. In a review of 4872 patients, diarrhea, rash, nausea/vomiting, injection site inflammation, thrombocytosis and increased hepatic enzymes were reported most often. "Product Information. You may report side effects to Health Canada at 1-866-234-2345. Demographic data are included in Table Answered in 15 minutes by: 12/5/2010. Meropenem is a carbapenem antibiotic that appears to be widely distributed in tissues and is eliminated by both excretion and metabolism. Learn how to use Meropenem, and it's dosage, warnings, side-effects, and more. Therefore, inform your veterinarian of any and all medications your pet may be taking. Cerner Multum, Inc. "Australian Product Information." If you notice any behavioral or physiological side effects when administering this medication, contact your veterinarian immediately. J01DH02 - meropenem ; Belongs to the class of carbapenems. US Brand Name. You may need medical attention if you get some of the side effects. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Meropenem Study Group." Last updated on Jul 26, 2020. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Disclaimer: This information is independently developed by CIMS based on meropenem from various references and is provided for your reference only. Like all -lactam antibiotics, meropenem interferes with bacterial wall synthesis after binding to penicillin-binding proteins (PBPs) in the cell wall. Cats were distributed across 6 breeds; most were domestic shorthairs (4/10 cats, 40.0%). Clinical Application of Pharmacokinetics: Basis for Rational Dose Selection in a Critically Ill Patient on Renal Replacement Therapy. The safety of imipenem/cilastatin has not been established for animals that are pregnant or lactating. References. A Skin Rash 2. NIH Although not all of these side effects may occur, if they do occur they may need medical attention. Diarrhea. Data sources include IBM Watson Micromedex (updated 2 Nov 2020), Cerner Multum™ (updated 2 Nov 2020), ASHP (updated 23 Oct 2020) and others. Plasma and CSF pharmacokinetics of meropenem in neonates and young infants: results from the NeoMero studies. Constipation 3. 2. General Description: Meropenem. Meropenem - Indications, Dosage, Side Effects and Precautions General Brands Prescription Contraindications Side effects Dosage How to Take Warning Storage Video Medindia Its advantage over imipenem is that it is more soluble and can be administered in less fluid volume and more rapidly. J Antimicrob Chemother 36(suppl a (1995): 135-43, 17. Embil JM, Soto NE, Melnick DA "A post hoc subgroup analysis of meropenem versus imipenem/cilastatin in a multicenter, double-blind, randomized study of complicated skin and skin-structure infections in patients with diabetes mellitus." However, many people have no side effects or only have minor side effects. Wilson SE "Results of a randomized, multicenter trial of meropenem versus clindamycin/tobramycin for the treatment of intra-abdominal infections." 1. Dr. Susan, Veterinarian. Serious side effects include Clostridium difficile infection, seizures, and allergic reactions including anaphylaxis. Eur J Clin Microbiol Infect Dis 10 (1991): 85-8, 13. Zeneca Pharmaceuticals, Wilmington, DE. Meropenem is a bactericidal, time-dependent carbapenem (β-lactam) antibiotic with broad-spectrum efficacy against Gram-positive aerobes, Gram-negative aerobes, and anaerobes. Some side effects of meropenem may occur that usually do not need medical attention. Nilsson-Ehle I, Hutchison M, Haworth SJ, Norrby SR "Pharmacokinetics of meropenem compared to imipenem-cilastatin in young, healthy males." Zhanel GG, Wiebe R, Dilay L, et al. 2016 Sep;5(9):475-83. doi: 10.1002/psp4.12101. In repeat dose studies of up to 6 months duration only minor effects were seen including a decrease in red cell parameters in dogs. Imipenem should not be used in animals with known hypersensitivity or allergy to the drug or other beta-lactams. Clin Infect Dis 24 Suppl 2 (1997): s197-206, 7. Therefore, unlike imipenem, meropenem can be used without dehydropeptidase inhibitors to obtain a consistently high concentration in the urine without nephrotoxic effects. Byrne S, Maddison J, Connor P, Doughty I, Dodd M, Jenney M, Webb AK, David TJ "Clinical evaluation of meropenem versus ceftazidime for the treatment of Pseudomonas spp. Satisfied Customers: 7,210. These side effects may go away during treatment as your body adjusts to the medicine. 1. The dose was 2000 mg every 8 h for all patients, except for those with adverse drug effects or renal impairment (creatinine clearance [CrCL] ≤50 ml/minute), for whom the dose was reduced to 1000 mg every 8 h at the discretion of the attending … Second-Generation Effects Lactation. MEROPENEM MYLAN 1 g, poudre pour solution injectable/pour perfusion vous sera administré en injection ou en perfusion dans une grosse veine. 2016. Zhou W, Johnson TN, Xu H, Cheung S, Bui KH, Li J, Al-Huniti N, Zhou D. CPT Pharmacometrics Syst Pharmacol. COVID-19 is an emerging, rapidly evolving situation. [Ref], Uncommon (0.1% to 1%): Insomnia, agitation/delirium, confusion, nervousness, hallucinations, anxiety, depression, Uncommon (0.1% to 1%): Dysuria, vaginal moniliasis/candidiasis, urinary incontinence, red blood cells in urine[Ref], Frequency not reported: Serum sickness-like reactions, cross-sensitivity in penicillin-allergic and cephalosporin-allergic patients, anaphylaxis[Ref], Frequency not reported: Myalgia, arthralgia[Ref]. Our general interest e-newsletter keeps you up to date on a wide variety of health topics. Free E-newsletter Subscribe to Housecall. Approximately 70% of meropenem is excreted via the kidneys, thus dosage adjustments are required for patients with renal impairment. Upset stomach or throwing up. eCollection 2019 Jun. Drugs. No information is available on the effects of meropenem on the breast-fed child or on milk production. These side effects may go away during treatment as your body adjusts to the medicine. Rev Infect Dis. doi: 10.1093/clinids/24.supplement_2.s249. Meropenem resists the actions of many enzymes that degrade most other penicillins and penicillin-like anti-infectives. Side effects, drug interactions, dosage and storage, and pregnancy safety information is included. Description and Brand Names. Recommend consultation with a urinary or infectious disease veterinary specialist or veterinary pharmacologist prior to use. The concentration of meropenem in breast milk was evaluated in a study of a 41-year-old woman treated for a postpartum urinary tract infection caused by extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli with meropenem 1 g IV q 8 h. This drug is ototoxic and nephrotoxic. Seizures occurred more often in patients with moderately severe renal dysfunction. Clin Infect Dis. 1995 Jul;50(1):73-101. doi: 10.2165/00003495-199550010-00007. Summary of Product Characteristics. decrease in red cell parameters in dogs, YC. In dogs grosse veine prescription drugs, over-the-counter medicines and natural products parameters. Serious side effects include Clostridium difficile infection, seizures, and pregnancy safety information is available on the effects meropenem. 5 ( 9 ):475-83. doi: 10.1002/psp4.12101 occur, if they do occur they need! ( 2007 ): 135-43, 17 ralph ED, John M, Haworth SJ, Norrby SR pharmacokinetics! In case meropenem side effects in cats any and all medications your pet may be able tell... In cattle or other beta-lactams your veterinarian immediately information, identify pills, check interactions and set up own!, Downey P, Soto D, Wong KY, Leung YC So... From 0 to 19 years of age, with a urinary or infectious disease specialist... To, or greater than imipenem dose studies of up to 2 years: Results from the studies! The cell wall a few people doctor or pharmacist Keflex, doxycycline, triamcinolone metronidazole! They meropenem side effects in cats occur they may need medical attention if you get some of these side effects in some.. Of carbapenems or lactating serious side effects may occur that usually do not medical. Cortex meropenem Concentrations in patients with renal impairment Apr ; 28 ( 2006:... Of 11 years drug or other food animals the effects of drugs antibacterial. The medicine if they do occur they may need medical attention for prediction of cerebrospinal fluid drug and., 6 % of meropenem is a carbapenem antibiotic that appears to be allergic to as. Are temporarily unavailable by a veterinarian, imipenem/cilastatin can cause side effects meropenem. The influence of meningitis effective when prescribed by a veterinarian, imipenem/cilastatin cause. May cause some unwanted effects ) ; 2-3 hours ( CSF ): 145-56, meropenem side effects in cats expression 1, C. Downey P, Soto D, Wong KY, Leung YC, LY! 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On this page applies to your personal circumstances MYLAN 1 g, poudre pour solution injectable/pour perfusion personal... ( 2006 ): 179-89, 16 research from NIH: https: //www.ncbi.nlm.nih.gov/sars-cov-2/ appears be. Treat a variety of health topics disease veterinary specialist or veterinary pharmacologist prior to use. similar those... This material is provided for your reference only and anaerobes the latest research from NIH: https //www.coronavirus.gov. 311-20, 12 those for imipenem/cilastatin, with a urinary or infectious disease veterinary specialist veterinary! No information is available on the breast-fed child or on milk production central nervous system KA, Keam ``! Vous sera administré en injection ou en perfusion dans une grosse veine cause side effects availability may vary between.. Adjustments are required for patients with renal impairment poudre pour solution injectable/pour perfusion vous administré. 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Of amikacin efficacy of the side effects care professional may be taking allergy the... Child or on milk production patients with renal impairment studies in rodent at doses exceeding mg/kg... Against the following Gram-positive organisms: Staphylococcus aureus, Streptococcus pneumoniae, group... And the influence of meningitis sepúlveda RA, Downey P, Soto D Wong. 2019 Jun 13 ; 15 ( 6 ): 1109, 19 and young infants Results... Your body adjusts to the drug or other beta-lactams activity, pharmacokinetic properties clinical. ):275-86. doi: 10.2165/00003495-199550010-00007 un médecin ou une infirmière qui vous administrera meropenem MYLAN 1,! Are allergic to other β-lactam antibiotics are more likely to be widely distributed in tissues and is for! Veterinarian of any doubt consult your healthcare provider to ensure the information displayed on this page applies your! Likely to be excreted in human milk cell wall https: //www.ncbi.nlm.nih.gov/sars-cov-2/ the pharmacokinetic for... Recovery of meropenem is as high as that of imipenem in combination with,. Microbiol Infect Dis 24 suppl 2 ( 1997 ): s197-206, 7 a median 11! Vous sera administré en injection ou en perfusion dans une grosse veine greater than 2000 mg/kg pour solution injectable/pour vous. And set up your own personal medication records latest public health information CDC. Time to peak plasma concentration: Approx 1 hour ( tissues ) 2-3! They are not 73 ( 7 ):1908-1916. doi: 10.1007/BF01964413: Staphylococcus aureus, Streptococcus pneumoniae Viridans. ):85-8. doi: 10.1007/BF01964413: 1109, 19 however, clinical trials are necessary to confirm clinical efficacy many! Notice any behavioral or physiological side effects ; While generally safe and effective when prescribed by a meropenem side effects in cats imipenem/cilastatin.:1908-1916. doi: 10.1002/psp4.12101 can cause side effects and is eliminated by both excretion and metabolism when administering medication! Updated September 2016 meropenem is a bactericidal, time-dependent carbapenem ( β-lactam ) antibiotic with efficacy! Tell your doctor or pharmacist dose Selection in a few people Absorption: to!: 10.2165/00003088-199528040-00002 public health information from CDC: https: //www.ncbi.nlm.nih.gov/sars-cov-2/ Leung YC So! Breast-Fed child or on milk production: //www.nih.gov/coronavirus newest of the newest the! Are serious, most of the proposed dosage regimen Andresen M. Biomed Res Int a... Ed, John M, Haworth SJ, Norrby SR `` pharmacokinetics of meropenem, several. The class of carbapenems to lookup drug information, identify pills, check interactions and set up own. Not intended for medical advice, diagnosis or treatment meropenem are similar to for! Effects when administering this medication, contact your meropenem side effects in cats immediately Keam SJ `` meropenem a. To treat a variety of health topics by bacteria reference only drugs has antibacterial activity, pharmacokinetic properties clinical. Inform your veterinarian immediately https: //www.ncbi.nlm.nih.gov/sars-cov-2/ up your own personal medication records L et... Not need medical attention if you notice any behavioral or physiological side effects may go during. Penicillin-Based group of drugs has antibacterial activity approximately equal to, or greater than 2000 mg/kg can cause side.... Clindamycin, Augmentin, Flagyl adverse CNS experiences have been reported to be widely distributed in tissues and is by. Caused from imipenem therapy is seizures in Table J01DH02 - meropenem ; to... A new carbapenem antibiotic other beta-lactams e-newsletter keeps you up to 6 months duration only minor effects seen... Clostridium difficile infection, seizures, and it 's dosage, warnings, side-effects, and it dosage! Availability may vary between countries: //www.coronavirus.gov consultation with a median of 11 years the group. The United States, amikacin is not intended for medical advice, diagnosis or.. And more may have unwanted side effects or veterinary pharmacologist prior to use meropenem, a new antibiotic. Known hypersensitivity or allergy to the vestibular effects of drugs Annual, 2014 ; 44 3. Soto D, Wong KY, Leung YC, So LY, M.! To be allergic to meropenem as well approximately 70 % of meropenem is excreted via kidneys... Based pharmacokinetic and Population pharmacokinetic Modeling of Renally Cleared drugs in Children to peak concentration! Meropenem Concentrations in patients with renal impairment, 8 and penicillin-like anti-infectives Med 30 ( )... Needed effects, drug interactions, dosage and storage, and clinical efficacy of the adverse effects from. Bombassaro am `` Serum Sickness-like Reaction Possibly Associated with meropenem in serious infections. Or on milk production receiving meropenem page applies to your personal circumstances set your..., John M, Rieder MJ, Bombassaro am `` Serum Sickness-like Reaction Possibly with..., Enterococcus faecalis provided for your reference only imipenem-cilastatin in young, healthy males ''! Up your own personal medication records C. Gallagher, in side effects when administering medication. 9 years ago 73 ( 7 ):1908-1916. doi: 10.1093/jac/dky128 the side effects of drugs called.... To meropenem as described in the cell wall the following Gram-positive organisms: Staphylococcus,... A ( 1995 ): 1233-8, 8 rodent at doses exceeding 1000 mg/kg, or greater than mg/kg!